Giants vs. Reds Prediction, Odds, Picks - April 8

Data Skrive

The San Francisco Giants and Cincinnati Reds will meet on Tuesday at Oracle Park, at 9:45 p.m. ET, with Willy Adames and Spencer Steer among those expected to step up at the plate. The Reds are +101 moneyline underdogs for this matchup with the favored Giants (-120). San Francisco is a 1.5-run favorite (at +173 odds). The over/under is 7.5 runs for the game (with -108 odds to go over and -112 odds on the under).

Here is everything you need from a betting perspective on the Giants-Reds game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Reds Game Information & Odds

When: Tuesday, April 8, 2025 at 9:45 p.m. ET
Where: Oracle Park in San Francisco, California
How to watch on TV: NBCS-BA and FDSOH

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Giants -120 +101 7.5 -108 -112 -1.5 +173 -214

Giants vs. Reds Prediction

Score Prediction: Giants 4, Reds 3
Total Prediction: Under 7.5 runs
Win Probabilities: Giants 59%, Reds 41%

Giants vs. Reds Betting Insights

The Giants have been listed as the favorite five times this season and have won all of those games.
San Francisco is undefeated in five games this season when favored by -120 or more on the moneyline.
Oddsmakers have implied with the moneyline set for this matchup that the Giants have a 54.5% chance to win.
The Reds have won in two of the seven contests they have been named as odds-on underdogs this year.
This season, Cincinnati has been victorious two times in six chances when named as an underdog of at least +101 or longer on the moneyline.
Oddsmakers have implied with the moneyline set for this matchup that the Reds have a 49.8% chance of pulling out a win.

Giants Player Insights

The Giants’ best power option comes in the form of Wilmer Flores and his four-dinger 12-RBI season, both team highs.
In all of MLB, Flores ranks sixth in home runs and fourth in RBI.
Flores carries a four-game hitting streak into this matchup. During his last five outings he is hitting .278 with a home run and four RBI.
Heliot Ramos is hitting .308 with three doubles, three home runs and a walk.
Of all major league hitters, Ramos is 17th in homers and 17th in RBI.
Ramos enters this matchup looking for his 10th game in a row with a hit. During his last nine outings he is batting .308 with three doubles, three home runs, a walk and nine RBI.
Jung Hoo Lee has put up a team-best batting average of .344.
Lee has at least one base hit in seven straight games. During his last eight games he is batting .344 with six doubles, three walks and three RBI.
Matt Chapman has two doubles, two home runs and seven walks while hitting .281.