Houston Astros vs. Los Angeles Angels odds, tips and betting trends | April 12

At Daikin Park on Saturday, the Los Angeles Angels (8-5) meet the Houston Astros (6-7), with first pitch at 7:10 p.m. ET.

The Astros are a home favorite (-141) against the Angels (+119). The matchup on the mound for this contest is set with the Houston Astros looking to Ryan Gusto (1-0), and Tyler Anderson answering the bell for the Los Angeles Angels.

These clubs meet again after the Astros defeated the Angels 14-3 yesterday. Ronel Blanco picked up the win for the Astros (5.0 IP, 2 R, 4 H, 7 K), and Yainer Diaz led the way offensively (3-for-5 with a double, a home run and five RBI). Jack Kochanowicz (4.2 IP, 6 R, 6 H, 1 K) was credited with the loss for the Angels.

Ahead of the Astros vs. Angels matchup, here’s what you need to get ready for Saturday’s baseball action, including viewing options.

Houston Astros vs. Los Angeles Angels odds, line and spread

MLB odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 3:19 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Favorite: Astros (-141, bet $141 to win $100)
  • Underdog: Angels (+119, bet $100 to win $119)
  • Over/under: 8.5

Astros vs. Angels: Game time and live stream info

  • Game day: Saturday, April 12, 2025
  • Game time: 7:10 p.m. ET
  • Location: Houston, Texas
  • Stadium: Daikin Park
  • TV channel: SCHN and FDSSC
  • Live stream: Watch LIVE with Fubo! (Regional restrictions may apply)

Watch Astros vs. Angels on Fubo!Astros stats and trends

Astros betting records

  • The Astros have entered the game as favorites seven times this season and won three of those games.
  • Houston has entered three games this season favored by -141 or more and is 1-2 in those contests.
  • The oddsmakers’ moneyline implies a 58.5% chance of a victory for the Astros.
  • Houston and its opponents have hit the over in five of its 13 games with a total this season.
  • The Astros have an ATS record of 6-7-0 in 13 games with a spread this season.

Ryan Gusto (Astros probable starter)

  • Gusto starts for the first time this season for the Astros.
  • The 26-year-old righty is making his MLB debut.
  • In four appearances this season, he has a 1.13 ERA and 10.1 strikeouts per nine innings, while opponents are hitting .179 against him.
  • The Angels rank eighth in run scoring in the league (68) this season and are batting .236 while hitting 25 home runs (third in the league).

Astros batting stats

  • The Astros’ 10 home runs rank 22nd in Major League Baseball.
  • Hitters for Houston have combined to rank 26th in MLB with a team slugging percentage of just .325 this season.
  • The Astros’ .227 batting average ranks 20th in the league this season.
  • Houston ranks 17th in the majors with 52 total runs scored this season.
  • The Astros have an OBP of .313 this season, which ranks 12th in MLB.
  • Houston ranks 16th in MLB in strikeouts per game with an average of 9.1 whiffs per contest.

Angels stats and trends

Angels betting records

  • The Angels have been chosen as underdogs in 10 games this year and have walked away with the win six times (60%) in those games.
  • This season, Los Angeles has come away with a win three times in five chances when named as an underdog of at least +119 or worse on the moneyline.
  • The Angels have an implied victory probability of 45.7% according to the moneyline set by oddsmakers for this matchup.
  • Contests with Los Angeles has gone over the total set by oddsmakers in nine of 13 chances this season.
  • The Angels are 7-6-0 against the spread in their 13 games with a line set by sportsbooks this season.

Tyler Anderson (Angels probable starter)

  • The Angels will look to Anderson (0-0) to open the game and make his third start of the season.
  • The lefty last appeared on Sunday against the Cleveland Guardians, when he went five innings, allowing two earned runs while giving up one hit.
  • In two games this season, he has a 4.50 ERA and 8.1 strikeouts per nine innings while opponents are hitting .200 against him.
  • Anderson will look to go five or more innings for his third straight start. He’s averaging five frames per outing.
  • The opposing Astros offense has the 26th-ranked slugging percentage (.325) and ranks 22nd in home runs hit (10) in all of MLB. They have a collective .227 batting average, and are 19th in the league with 99 total hits and 17th in MLB action scoring 52 runs.

Angels batting stats

  • The Angels rank third in baseball with 25 home runs. They average 1.9 per game.
  • So far this year, Los Angeles’ .453 slugging percentage is second-best in baseball.
  • The Angels have the 14th-ranked batting average in the league (.236).
  • Los Angeles scores the eighth-most runs in baseball (68 total, 5.2 per game).
  • The Angels’ .307 on-base percentage is 19th in the majors.

Watch the MLB on Fubo!

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